Native Human Serum Haptoglobin

Cat.No.: HP-8153H
Product Overview: Human Serum Haptoglobin was purified from Human Serum.
Description: Haptoglobin is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen). Haptoglobin is a serum protein that consists of two alpha and two beta chains connected by disulfide bridges. Human haptoglobin acts as a hemoglobin scavenger and has been associated with protease inhibitory activity. Human Haptoglobin is a positive acute phase reactant, the levels of which increase significantly in human(s) in response to inflammation, tissue injury or disease.
Source: Human Serum
Species: Human
Form: Lyophilized
Purity: >98% by SDS-PAGE
Stability: 2 years
Storage: 2-8 °C
Gene Name: HP haptoglobin [ Homo sapiens ]
Official Symbol: HP
Synonyms: HP; haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide; BP; HPA1S; HP2ALPHA2; MGC111141;
Gene ID: 3240
mRNA Refseq: NM_001126102
Protein Refseq: NP_001119574
MIM: 140100
UniProt ID: P00738
Chromosome Location: 16q22.2
Pathway: amb2 Integrin signaling, organism-specific biosystem;
Function: catalytic activity; hemoglobin binding; serine-type endopeptidase activity;

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