Native Human Serum Haptoglobin

• Cat.No.: HP-8153H
• Product Overview: Human Serum Haptoglobin was purified from Human Serum.

Specification

• Description: Haptoglobin is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen). Haptoglobin is a serum protein that consists of two alpha and two beta chains connected by disulfide bridges. Human haptoglobin acts as a hemoglobin scavenger and has been associated with protease inhibitory activity. Human Haptoglobin is a positive acute phase reactant, the levels of which increase significantly in human(s) in response to inflammation, tissue injury or disease.
• Source: Human Serum
• Species: Human
• Form: Lyophilized
• Purity: >98% by SDS-PAGE
• Stability: 2 years
• Storage: 2-8 °C

Gene Information

• Gene Name: HP haptoglobin [ Homo sapiens ]
• Official Symbol: HP
• Synonyms: HP; haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide; BP; HPA1S; HP2ALPHA2; MGC111141
• Gene ID: 3240
• mRNA Refseq: NM_001126102
• Protein Refseq: NP_001119574
• MIM: 140100
• UniProt ID: P00738
• Chromosome Location: 16q22.2
• Pathway: amb2 Integrin signaling, organism-specific biosystem
• Function: catalytic activity; hemoglobin binding; serine-type endopeptidase activity