Native Human Neutrophil Elastase (ELA-2)
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Cat.No. : | ELANE-8236H |
Product Overview : | Human Neutrophil Elastase (ELA-2) was purified from Human Neutrophils. |
Description : | Human Neutrophils, also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. Human Neutrophil(s), have a multilobed nucleus and neutrophilic granules. Neutrophil(s) are phagocytes and have an important role in engulfing and killing extracellular pathogens. |
Source : | Human Neutrophils |
Species : | Human |
Form : | Lyophilized from 50 mM acetate buffer |
Purity : | >95% by SDS-PAGE |
Unit Definition : | One unit will hydrolyze one micromole of Methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37 °C and pH 7.5. |
Stability : | 2 years |
Gene Name : | ELANE elastase, neutrophil expressed [ Homo sapiens ] |
Official Symbol : | ELANE |
Synonyms : | ELANE; elastase, neutrophil expressed; ELA2, elastase 2, neutrophil; neutrophil elastase; HLE; HNE; leukocyte elastase; medullasin; NE; elastase-2; PMN elastase; elastase 2, neutrophil; human leukocyte elastase; polymorphonuclear elastase; bone marrow se |
Gene ID : | 1991 |
mRNA Refseq : | NM_001972 |
Protein Refseq : | NP_001963 |
MIM : | 130130 |
UniProt ID : | P08246 |
Chromosome Location : | 19p13.3 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Systemic lupus erythematosus, organism-specific biosystem; Systemic lupus erythematosus, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; |
Function : | bacterial cell surface binding; cytokine binding; endopeptidase activity; heparin binding; peptidase activity; protease binding; protein binding; serine-type endopeptidase activity; |
◆ Recombinant Protein
ELANE-1197H | Recombinant Human ELANE Protein, GST-tagged | +Inquiry |
ELANE-2172H | Recombinant Human ELANE Protein, His-tagged | +Inquiry |
ELANE-3222H | Recombinant Human ELANE Protein, GST-tagged | +Inquiry |
ELANE-902D | Recombinant Dog ELANE Protein, His-tagged | +Inquiry |
Elane-1419M | Recombinant Mouse Elane Protein, His-tagged | +Inquiry |
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◆ Native Protein
ELANE-3221H | Native Human ELANE Protein | +Inquiry |
ELANE-27537TH | Native Human ELANE | +Inquiry |
ELANE-8104H | Native Human Neutrophil Elastase | +Inquiry |
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◆ Lysates
ELANE-2381MCL | Recombinant Mouse ELANE cell lysate | +Inquiry |
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◆ Assay kits
Kit-0322 | Neutrophil Elastase Activity Assay Kit | +Inquiry |
Kit-0323 | Neutrophil elastase colorimetric drug discovery Kit | +Inquiry |
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