"CAPN1" Related Products


Native Human CAPN1

Cat.No. : CAPN1-8448H
Description : Ca2+-dependent cysteine proteinase with low Ca2+ requirement (half maximal activation = 2 μM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.
Source : Human
Species : Human
Form : In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
Bio-activity : >1000 units/mg protein
Molecular Mass : 112.0 kDa
Purity : ≥95% by SDS - PAGE
Storage : Store at –70°C, stable for at least 1 year as supplied. Avoid freeze/thaw cycles.
Shipping : gel pack
Gene Name : CAPN1 calpain 1, (mu/I) large subunit [ Homo sapiens ]
Official Symbol : CAPN1
Synonyms : CAPN1; calpain 1, (mu/I) large subunit; calpain-1 catalytic subunit; CANP; CANPL1; muCANP; muCL; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein; CANP1;
Gene ID : 823
mRNA Refseq : NM_001198868
Protein Refseq : NP_001185797
MIM : 114220
UniProt ID : P07384
Chromosome Location : 11q13
Pathway : Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Integrin-mediated cell adhesion, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem;
Function : calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity; protein binding;

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