"CAPN1" Related Products

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Native Human CAPN1

Cat.No.: CAPN1-8448H
Description: Ca2+-dependent cysteine proteinase with low Ca2+ requirement (half maximal activation = 2 μM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.
Source: Human
Species: Human
Form: In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
Bio-activity: >1000 units/mg protein
Molecular Mass: 112.0 kDa
Purity: ≥95% by SDS - PAGE
Storage: Store at –70°C, stable for at least 1 year as supplied. Avoid freeze/thaw cycles.
Shipping: gel pack
Gene Name: CAPN1 calpain 1, (mu/I) large subunit [ Homo sapiens ]
Official Symbol: CAPN1
Synonyms: CAPN1; calpain 1, (mu/I) large subunit; calpain-1 catalytic subunit; CANP; CANPL1; muCANP; muCL; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein; CANP1;
Gene ID: 823
mRNA Refseq: NM_001198868
Protein Refseq: NP_001185797
MIM: 114220
UniProt ID: P07384
Chromosome Location: 11q13
Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Integrin-mediated cell adhesion, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem;
Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity; protein binding;

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