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Recombinant Human AHCYL1, His-tagged

Cat.No. : AHCYL1-8459H
Product Overview : AHCY Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 452 amino acids (1-432 a.a.) and having a molecular mass of 49.8 kDa. The AHCY is fused to 20 amino acid His-Tag at N-terminus and purified by chromatogra
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Description : AHCY is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia.
Source : E. coli
Species : Human
Tag : His
Form : Sterile filtered solution in 20 mM Tris, pH 8 with 10 % glycerol.
Molecular Mass : 49.8 kDa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYSASKPLKGARI AGCLHMTVET AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVYAWKGETDEEY LWCIEQTLYF KDGPLNMILD DGGDLTNLIH TKYPQLLPGI RGISEETTTGVHNLYKMMAN GILKVPAINV NDSVTKSKFD NLYGCRESLI DGIKRATDVM IA
Purity : ≥95% by SDS - PAGE
Storage : Store at -20°C. Avoid freeze-thaw cycles.
Shipping : Blue Ice
Gene Name : AHCYL1 adenosylhomocysteinase-like 1 [ Homo sapiens ]
Official Symbol : AHCYL1
Synonyms : AHCYL1; adenosylhomocysteinase-like 1; S adenosylhomocysteine hydrolase like 1; putative adenosylhomocysteinase 2; inositol 1; 4; 5 trisphosphate receptor binding protein; IRBIT; XPVKONA; adoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosyl homocysteine hydrolase homolog; dendritic cell expressed AHCY-like protein; S-adenosylhomocysteine hydrolase-like protein 1; inositol 1,4,5-trisphosphate receptor-binding protein; DCAL; PRO0233;
Gene ID : 10768
mRNA Refseq : NM_001242673
Protein Refseq : NP_001229602
MIM : 607826
UniProt ID : O43865
Chromosome Location : 1p13
Pathway : Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; cysteine biosynthesis III (mammalia), organism-specific biosystem; methionine degradation I (to homocysteine), organism-specific biosystem;
Function : adenosylhomocysteinase activity; hydrolase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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