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Recombinant Human CRYAB protein

Cat.No. : CRYAB-9158H
Product Overview : Recombinant Human CRYAB(1-175 aa) was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.
Source : E. coli
Species : Human
Form : Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50mM NaCl, 1mM EDTA
Molecular Mass : 20.1kDa (175aa)
AA Sequence : MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK
Purity : > 95% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : CRYAB crystallin, alpha B [ Homo sapiens ]
Official Symbol : CRYAB
Synonyms : CRYAB; crystallin, alpha B; CRYA2; alpha-crystallin B chain; HSPB5; heat shock protein beta-5; rosenthal fiber component; heat-shock 20 kD like-protein; renal carcinoma antigen NY-REN-27; CTPP2;
Gene ID : 1410
mRNA Refseq : NM_001885
Protein Refseq : NP_001876
MIM : 123590
UniProt ID : P02511
Chromosome Location : 11q22.3-q23.1
Pathway : Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function : protein binding; protein homodimerization activity; structural constituent of eye lens; unfolded protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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