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Recombinant Rat Msr1 protein(Trp79-Ser454), hFc-tagged

Cat.No. : Msr1-8792R
Product Overview : Recombinant Rat MSR1 (NP_001178868.1)(Trp79-Ser454) was expressed in HEK293, fused with the Fc region of Human IgG1 at the N-terminus.
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Source : HEK293
Species : Rat
Tag : N-hFc
Protein length : Trp79-Ser454
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant Rat MSR1/Fc comprises 636 amino acids and has a predicted molecular mass of 69.2 kDa. The apparent molecular mass of the protein is approximately 89 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Msr1 macrophage scavenger receptor 1 [ Rattus norvegicus ]
Official Symbol : Msr1
Synonyms : MSR1; macrophage scavenger receptor 1; macrophage scavenger receptor types I and II; RGD1564316;
Gene ID : 498638
mRNA Refseq : NM_001191939
Protein Refseq : NP_001178868

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the primary function of the MSR1 protein, and in which cellular processes does it play a crucial role? 09/24/2020

MSR1 (Macrophage Scavenger Receptor 1) is involved in the recognition and clearance of modified low-density lipoproteins (LDL) by macrophages, playing a critical role in lipid homeostasis.

How does MSR1 contribute to the resolution of inflammation, and what mechanisms are involved in its anti-inflammatory effects? 02/10/2020

MSR1 contributes to the resolution of inflammation by promoting the clearance of apoptotic cells and debris. Its anti-inflammatory effects involve modulating cytokine production and signaling.

What role does MSR1 play in antigen presentation and T-cell activation within the immune system? 06/21/2019

MSR1 participates in antigen presentation by macrophages, influencing T-cell activation. This role connects MSR1 to adaptive immune responses.

What is the relationship between MSR1 and the clearance of amyloid-beta peptides, and how does this link to neurodegenerative diseases? 10/13/2018

MSR1 is involved in the clearance of amyloid-beta peptides associated with neurodegenerative diseases such as Alzheimer's. Its role in phagocytosis and clearance is crucial in the context of neuroinflammation.

How does MSR1 contribute to the immune response, and what are its implications in the context of inflammation and atherosclerosis? 01/31/2018

MSR1 modulates the immune response by regulating inflammatory signaling pathways. Its involvement in recognizing modified LDL in atherosclerotic plaques links it to inflammation and atherosclerosis.

Customer Reviews (3)

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Reviews
03/19/2022

    No more worries about protein sourcing. This product is a lifesaver in the lab.

    07/03/2020

      Outstanding service! Quick response to inquiries and prompt shipping. A+

      10/26/2019

        This is a must-have in any lab. Consistent quality and great results every time.

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