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Native Human AMY2A

Cat.No.: AMY2A-8353H
Product Overview: Native Human AMY2A was purified from Pancrease.
Description: Alpha amylase is a polysaccharide-hydrolyzing enzyme secreted in the pancreas and salivary glands. Increased serum levels are seen in acute pancreatitis: the amount of amylase in the blood rises within 3 to 6 hours of onset, peaking at up to 40 times the normal level (after 20 to 30 hours) with normal levels re-established within 2 to 8 days. High blood amylase levels may also be due to impaired glomerular filtration leading to reduced renal elimination.
Source: Pancrease
Species: Human
Form: Liquid in 0.1M TRIS buffer, pH 7.5, containing 0.15M NaCl, 1mM calcium chloride, 1mM benzamidine and 1mM pefabloc.
Unit Definition: One unit will catalyse the hydrolysis of one micromole of malto-pentaose, which through coupled reactions results in the formation of 5 micromoles of glucose-6- phosphate per minute at 37°C. Measured at 340nm as an equimolar amount of NADH produced by a coupled reaction.
Gene Name: AMY2A amylase, alpha 2A (pancreatic) [ Homo sapiens ]
Official Symbol: AMY2A
Synonyms: AMY2A; amylase, alpha 2A (pancreatic); AMY2, amylase, alpha 2A; pancreatic; pancreatic alpha-amylase; glycogenase; alpha-amylase; found in the pancreas; pancreatic amylase 2A; pancreatic amylase alpha 2A; amylase, pancreatic, alpha-2A; 1,4-alpha-D-glucan
Gene ID: 279
mRNA Refseq: NM_000699
Protein Refseq: NP_000690
MIM: 104650
UniProt ID: P04746
Chromosome Location: 1p21.1
Pathway: Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Digestion of dietary carbohydrate, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Pancreatic secretion, organism-specific biosystem;
Function: alpha-amylase activity; calcium ion binding; chloride ion binding; hydrolase activity, acting on glycosyl bonds;

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