"PARK7" Related Products

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Recombinant Human PARK7, GST-tagged

Cat. No. : PARK7-115H
Product Overview : Recombinant Human PARK7 fused with GST-tag at N-terminal, was expressed in E. coli.
Description : The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Source : E. coli
Molecular Mass : 19.9 kDa
Activity : Cleaved DJ-1 was assayed for protease activity.
Purity : Greater than 95%, as determined by SDS-PAGE.
Applications : ELISA, WB, Protease Activity Determination.
Storage : Purified DJ-1 is supplied as sterile and frozen at 1 mg/ml in 50 mM Tris-Cl/150mM NaCl, pH=8.0. Store at 2-4ºC for immediate use within 1-2 weeks or at –80ºC for up to 12 months. Avoid repeated freeze-thaw cycles.
OfficialSymbol : PARK7
PDB rendering basedon 1j42. :

Gene Name : PARK7 Parkinson disease (autosomal recessive, early onset) 7 [ Homo sapiens ]
Synonyms : PARK7; Parkinson disease (autosomal recessive, early onset) 7; DJ1; DJ-1; FLJ27376; FLJ34360; FLJ92274; Parkinson disease protein 7; oncogene DJ1; oncogene DJ1; protein DJ-1; OTTHUMP00000001350; OTTHUMP00000001351; OTTHUMP00000001348; OTTHUMP00000001349
Gene ID : 11315
mRNA Refseq : NM_001123377
Protein Refseq : NP_001116849
MIM : 602533
UniProt ID : Q99497
Chromosome Location : 1p36.23
Pathway : Parkinson's disease; Alpha-synuclein signaling
Function : peroxiredoxin activity; protein binding

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