Recombinant Human PNPLA2, GST-tagged

• Cat.No.: PNPLA2-325H
• Product Overview: Recombinant Human PNPLA2 (1 a.a. - 504 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Cat. No.: PNPLA2-325H
• Description: This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.
• Source: wheat germ
• Molecular Mass: 81.7 kDa
• Sequence: MFPREKTWNISFAGCGFLGVYYVGV ASCLREHAPFLVANATHIYGASAGA LTATALVTGVCLGEAGAKFIEVSKE ARKRFLGPLHPSFNLVKIIRSFLLK VLPADSHEHASGRLGISLTRVSDGE NVIISHFNSKDELIQANVCSGFIPV YCGLIPPSLQGVRYVDGGISDNLPL YELKNTITVSPFSGESDICPQDSST NIHELRVTNTSIQFNLRNLYRLSKA LFPPEPLVLREMCKQGYRDGLRFLQ RNGLLNRPNPLLALPPARPHGPEDK DQAVESAQAEDYSQLPGEDHILEHL PARLNEALLEACVEPTDLLTTLSNM LPVRLATAMMVPYTLPLESALSFTI RLLEWLPDVPEDIRWMKEQTGSICQ YLVMRAKRKLGRHLPSRLPEQVELR RVQSLPSVPLSCAAYREALPGWMRN NLSLGDALAKWEECQRQLLLGLFCT NVAFPPEALRMRAPADPAPAPADPA SPQHQLAGPAPLLSTPAPEARPVIG ALGL
• Purification: Glutathione Sepharose 4 Fast Flow
• Storage buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Applications: ELISA; WB
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Note: Best use within three months from the date of receipt of this protein.
• OfficialSymbol: PNPLA2

Gene Information

• Gene Name: PNPLA2 patatin-like phospholipase domain containing 2 [ Homo sapiens ]
• Synonyms: PNPLA2; patatin-like phospholipase domain containing 2; TGL; TTS2; PEDF-R; FP17548; TTS-2.2; DESNUTRIN; DKFZp667M109; 1110001C14Rik; triglyceride hydrolase; adipose triglyceride lipase; transport-secretion protein 2.2; pigment epithelium-derived factor; Patatin-like phospholipase domain-containing protein 2; EC 3.1.1.3; Adipose triglyceride lipase; Desnutrin; Transport-secretion protein 2; TTS2.2; Calcium-independent phospholipase A2; IPLA2-zeta; Pigment epithelium-derived factor
• Gene ID: 57104
• mRNA Refseq: NM_020376
• Protein Refseq: NP_065109
• MIM: 609059
• UniProt ID: Q96AD5
• Chromosome Location: 11p15.5
• Pathway: Acyl chain remodeling of DAG and TAG; Acylglycerol degradation; Fatty Acid Beta Oxidation; Glycerolipid metabolism
• Function: retinyl-palmitate esterase activity; triglyceride lipase activity