Recombinant Human PNPLA2, GST-tagged PNPLA2-325H

Recombinant Human PNPLA2, GST-tagged

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Cat. No. :	PNPLA2-325H
Product Overview :	Recombinant Human PNPLA2 (1 a.a. - 504 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ.
Description :	This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.
Source :	wheat germ
Molecular Mass :	81.7 kDa
Sequence :	MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTR VSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQ GYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVP EDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQ LAGPAPLLST PAPEARPVIG ALGL
Purification :	Glutathione Sepharose 4 Fast Flow
Storage buffer :	50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Applications :	ELISA; WB
Storage :	Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note :	Best use within three months from the date of receipt of this protein.
OfficialSymbol :	PNPLA2

Gene Name :	PNPLA2 patatin-like phospholipase domain containing 2 [ Homo sapiens ]
Synonyms :	PNPLA2; patatin-like phospholipase domain containing 2; TGL; TTS2; PEDF-R; FP17548; TTS-2.2; DESNUTRIN; DKFZp667M109; 1110001C14Rik; triglyceride hydrolase; adipose triglyceride lipase; transport-secretion protein 2.2; pigment epithelium-derived factor; Patatin-like phospholipase domain-containing protein 2; EC 3.1.1.3; Adipose triglyceride lipase; Desnutrin; Transport-secretion protein 2; TTS2.2; Calcium-independent phospholipase A2; IPLA2-zeta; Pigment epithelium-derived factor
Gene ID :	57104
mRNA Refseq :	NM_020376
Protein Refseq :	NP_065109
MIM :	609059
UniProt ID :	Q96AD5
Chromosome Location :	11p15.5
Pathway :	Acyl chain remodeling of DAG and TAG; Acylglycerol degradation; Fatty Acid Beta Oxidation; Glycerolipid metabolism
Function :	retinyl-palmitate esterase activity; triglyceride lipase activity