"AMACR" Related Products


Recombinant Human AMACR, MYC/DDK-tagged

Cat. No.: AMACR-106H
Product Overview: Recombinant Human AMACR fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
Description: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Source: HEK293 Cells
Molecular Mass: 42.2 kDa
Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
Storagebuffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Concentration: >50 ug/mL as determined by microplate BCA method
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage: Store at -800C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
OfficialSymbol: AMACR
Gene Name: AMACR alpha-methylacyl-CoA racemase [ Homo sapiens ]
Synonyms: AMACR; RACE; CBAS4; AMACRD; alpha-methylacyl-CoA racemase; EC; 2-methylacyl-CoA racemase
Gene ID: 23600
mRNA Refseq: NM_014324
Protein Refseq: NP_055139
MIM: 604489
UniProt ID: Q9UHK6
Chromosome Location: 5p13
Pathway: Metabolic pathways; Primary bile acid biosynthesis; Metabolism of lipids and lipoproteins
Function: alpha-methylacyl-CoA racemase activity; receptor binding

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