Recombinant Human A4GALT, GST-tagged

• Cat.No.: A4GALT-9186H
• Product Overview: Recombinant human A4GALT protein, fused to GST-tag, was expressed in E.coli and purified by GST-sepharose.

Specification

• Description: The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 41-353a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: A4GALT alpha 1,4-galactosyltransferase [ Homo sapiens ]
• Official Symbol: A4GALT
• Synonyms: A4GALT; alpha 1,4-galactosyltransferase; alpha 1,4 galactosyltransferase (globotriaosylceramide synthase, P blood group); lactosylceramide 4-alpha-galactosyltransferase; A14GALT; CD77 synthase; Gb3 synthase; Gb3S; globotriaosylceramide synthase; P(k); GB3 synthase; alpha4Gal-T1; P1/Pk synthase; P(k) antigen synthase; P blood group (P one antigen); alpha-1,4-N-acetylglucosaminyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase; P1; PK; A4GALT1
• Gene ID: 53947
• mRNA Refseq: NM_017436
• Protein Refseq: NP_059132
• MIM: 607922
• UniProt ID: Q9NPC4
• Chromosome Location: 22q13.2
• Pathway: Glycosphingolipid biosynthesis - globo series, organism-specific biosystem; Glycosphingolipid biosynthesis - globo series, conserved biosystem; Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer, organism-specific biosystem; Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: galactosyltransferase activity; lactosylceramide 4-alpha-galactosyltransferase activity; transferase activity, transferring glycosyl groups