Recombinant Human AATF, GST-tagged
Cat.No. : | AATF-9201H |
Product Overview : | Recombinant human AATF protein, fused to GST-tag, was expressed in E.coli and purified by GST-sepharose. |
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Description : | The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 7-212a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | AATF apoptosis antagonizing transcription factor [ Homo sapiens ] |
Official Symbol : | AATF |
Synonyms : | AATF; apoptosis antagonizing transcription factor; protein AATF; CHE 1; CHE1; DED; rb-binding protein Che-1; apoptosis-antagonizing transcription factor; CHE-1; |
Gene ID : | 26574 |
mRNA Refseq : | NM_012138 |
Protein Refseq : | NP_036270 |
MIM : | 608463 |
UniProt ID : | Q9NY61 |
Chromosome Location : | 17q12 |
Pathway : | Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signalling by NGF, organism-specific biosystem; p75 NTR receptor-mediated signalling, organism-specific biosystem; |
Function : | leucine zipper domain binding; protein binding; protein domain specific binding; sequence-specific DNA binding transcription factor activity; tau protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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