Recombinant Human ABP1, GST-tagged

• Cat.No.: ABP1-9255H
• Product Overview: Recombinant Human ABP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 400-751a.a.
• Description: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ABP1 amiloride binding protein 1 (amine oxidase (copper-containing)) [ Homo sapiens ]
• Official Symbol: ABP1
• Synonyms: ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-sensitive amine oxidase [copper-containing]; AOC1; DAO; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein-1; amiloride-sensitive amine oxidase; ABP; KAO; DAO1
• Gene ID: 26
• mRNA Refseq: NM_001091
• Protein Refseq: NP_001082
• MIM: 104610
• UniProt ID: P19801
• Chromosome Location: 7q34-qter
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; Tryptophan metabolism, organism-specific biosystem; Tryptophan metabolism, organism-specific biosystem; Tryptophan metabolism, conserved biosystem
• Function: calcium ion binding; cation channel activity; copper ion binding; diamine oxidase activity; drug binding; heparin binding; histamine oxidase activity; methylputrescine oxidase activity; oxidoreductase activity; primary amine oxidase activity; propane-1,3-