Recombinant Human ACADS, His-tagged

• Cat.No.: ACADS-9269H
• Product Overview: Recombinant Human ACADS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-412a.a.
• Description: This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain [ Homo sapiens ]
• Official Symbol: ACADS
• Synonyms: ACADS; acyl-CoA dehydrogenase, C-2 to C-3 short chain; acyl Coenzyme A dehydrogenase, C 2 to C 3 short chain; short-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD3; SCAD; butyryl-CoA dehydrogenase; unsaturated acyl-CoA reductase; short-chain acyl-CoA dehydrogenase; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain; mitochondrial short-chain specific acyl-CoA dehydrogenase
• Gene ID: 35
• mRNA Refseq: NM_000017
• Protein Refseq: NP_000008
• MIM: 606885
• UniProt ID: P16219
• Chromosome Location: 12q24.31
• Pathway: Beta oxidation of butanoyl-CoA to acetyl-CoA, organism-specific biosystem; Beta oxidation of hexanoyl-CoA to butanoyl-CoA, organism-specific biosystem; Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem
• Function: acyl-CoA dehydrogenase activity; butyryl-CoA dehydrogenase activity; fatty-acyl-CoA binding; flavin adenine dinucleotide binding