| Cat.No.: | ASIC4-9282H |
| Product Overview: | Recombinant Human ASIC4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
| Antigen Description: | This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predom |
| Description: | This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. |
| Source: | E.coli |
| Species: | Human |
| Tag: | GST |
| Protein length: | C-term-350a.a. |
| Storage: | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer: | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name: | ASIC4 acid-sensing (proton-gated) ion channel family member 4 [ Homo sapiens (human) ] |
| Official Symbol: | ASIC4 |
| Synonyms: | ASIC4; acid-sensing (proton-gated) ion channel family member 4; ACCN4; BNAC4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4; HGNC:21263; Ensembl:ENSG00000072182; HPRD:16231; MIM:606715; Vega:OTTHUMG00000058928 |
| Gene ID: | 55515 |
| mRNA Refseq: | NM_182847.2 |
| Protein Refseq: | NP_878267.2 |
| MIM: | 606715 |
| UniProt ID: | Q96FT7 |
| Chromosome Location: | 2q35 |
| Pathway: | Ion channel transport, organism-specific biosystem; Stimuli-sensing channels, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem |
| Function: | ion channel activity; sodium channel activity; sodium ion transmembrane transporter activity |
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