Recombinant Human ASIC4, GST-tagged

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Recombinant Human ASIC4, GST-tagged

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Cat.No. : ASIC4-9282H
Product Overview : Recombinant Human ASIC4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Antigen Description : This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predom
Description : This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : ASIC4 acid-sensing (proton-gated) ion channel family member 4 [ Homo sapiens (human) ]
Official Symbol : ASIC4
Synonyms : ASIC4; acid-sensing (proton-gated) ion channel family member 4; ACCN4; BNAC4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4; HGNC:21263; Ensembl:ENSG00000072182; HPRD:16231; MIM:606715; Vega:OTTHUMG00000058928
Gene ID : 55515
mRNA Refseq : NM_182847.2
Protein Refseq : NP_878267.2
MIM : 606715
UniProt ID : Q96FT7
Chromosome Location : 2q35
Pathway : Ion channel transport, organism-specific biosystem; Stimuli-sensing channels, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
Function : ion channel activity; sodium channel activity; sodium ion transmembrane transporter activity

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