Recombinant Human ASIC4, GST-tagged

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Recombinant Human ASIC4, GST-tagged

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Cat.No. : ASIC4-9282H
Product Overview : Recombinant Human ASIC4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Antigen Description : This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predom
Description : This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : ASIC4 acid-sensing (proton-gated) ion channel family member 4 [ Homo sapiens (human) ]
Official Symbol : ASIC4
Synonyms : ASIC4; acid-sensing (proton-gated) ion channel family member 4; ACCN4; BNAC4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4; HGNC:21263; Ensembl:ENSG00000072182; HPRD:16231; MIM:606715; Vega:OTTHUMG00000058928
Gene ID : 55515
mRNA Refseq : NM_182847.2
Protein Refseq : NP_878267.2
MIM : 606715
UniProt ID : Q96FT7
Chromosome Location : 2q35
Pathway : Ion channel transport, organism-specific biosystem; Stimuli-sensing channels, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
Function : ion channel activity; sodium channel activity; sodium ion transmembrane transporter activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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