Recombinant Human ACTN1, GST-tagged
Cat.No. : | ACTN1-9339H |
Product Overview : | Recombinant Human ACTN1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-350a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ACTN1 actinin, alpha 1 [ Homo sapiens ] |
Official Symbol : | ACTN1 |
Synonyms : | ACTN1; actinin, alpha 1; alpha-actinin-1; actinin 1 smooth muscle; non-muscle alpha-actinin-1; F-actin cross-linking protein; alpha-actinin cytoskeletal isoform; FLJ40884; FLJ54432; |
Gene ID : | 87 |
mRNA Refseq : | NM_001102 |
Protein Refseq : | NP_001093 |
MIM : | 102575 |
UniProt ID : | P12814 |
Chromosome Location : | 14q24.1 |
Pathway : | Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell junction organization, organism-specific biosystem; |
Function : | actin binding; actin filament binding; calcium ion binding; integrin binding; ion channel binding; protein binding; protein domain specific binding; vinculin binding; |
Products Types
◆ Recombinant Protein | ||
ACTN1-142R | Recombinant Rat ACTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTN1-435H | Recombinant Human ACTN1 Protein, His-tagged | +Inquiry |
Actn1-432M | Recombinant Mouse Actn1 Protein, MYC/DDK-tagged | +Inquiry |
ACTN1-270H | Recombinant Human ACTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTN1-486R | Recombinant Rat ACTN1 Protein | +Inquiry |
◆ Native Protein | ||
ACTN1-162C | Native chicken ACTN1 | +Inquiry |
◆ Lysates | ||
ACTN1-9056HCL | Recombinant Human ACTN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket