Recombinant Human ADH4, GST-tagged
| Cat.No. : | ADH4-9419H |
| Product Overview : | Recombinant Human ADH4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 1-380a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name : | ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide [ Homo sapiens ] |
| Official Symbol : | ADH4 |
| Synonyms : | ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide; alcohol dehydrogenase 4; ADH 2; aldehyde reductase; alcohol dehydrogenase class II pi chain; ADH-2; |
| Gene ID : | 127 |
| mRNA Refseq : | NM_000670 |
| Protein Refseq : | NP_000661 |
| MIM : | 103740 |
| UniProt ID : | P08319 |
| Chromosome Location : | 4q22 |
| Pathway : | Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; |
| Function : | NAD binding; NADPH:quinone reductase activity; alcohol dehydrogenase (NAD) activity; alcohol dehydrogenase activity, zinc-dependent; alditol:NADP+ 1-oxidoreductase activity; all-trans retinal binding; benzaldehyde dehydrogenase activity; metal ion binding |
Products Types
| ◆ Lysates | ||
| ADH4-29HCL | Recombinant Human ADH4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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