Recombinant Human ADHFE1, His-tagged

• Cat.No.: ADHFE1-9422H
• Product Overview: Recombinant Human ADHFE1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-255a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ADHFE1 alcohol dehydrogenase, iron containing, 1 [ Homo sapiens ]
• Official Symbol: ADHFE1
• Synonyms: ADHFE1; alcohol dehydrogenase, iron containing, 1; hydroxyacid-oxoacid transhydrogenase, mitochondrial; ADHFe1; FLJ32430; alcohol dehydrogenase 8; Fe-containing alcohol dehydrogenase 1; alcohol dehydrogenase iron-containing protein 1; HOT; ADH8; HMFT2263; MGC48605
• Gene ID: 137872
• mRNA Refseq: NM_144650
• Protein Refseq: NP_653251
• MIM: 611083
• UniProt ID: Q8IWW8
• Chromosome Location: 8q12.3
• Pathway: Interconversion of 2-oxoglutarate and 2-hydroxyglutarate, organism-specific biosystem; Metabolism, organism-specific biosystem; Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem; The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem
• Function: hydroxyacid-oxoacid transhydrogenase activity; metal ion binding; oxidoreductase activity