The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.
Source :
E.coli
Species :
Human
Tag :
GST
Protein length :
1-350a.a.
Storage :
The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer :
1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
AKAP6; A kinase (PRKA) anchor protein 6; A-kinase anchor protein 6; ADAP6; AKAP100; KIAA0311; mAKAP; PRKA6; protein kinase A anchoring protein 6; AKAP-6; AKAP 100; A-kinase anchor protein 100 kDa; protein kinase A-anchoring protein 6; ADAP100; MGC165020;
G Protein Signaling Pathways, organism-specific biosystem;
Function :
enzyme binding; protein N-terminus binding; protein complex scaffold; protein kinase A binding; protein kinase A binding; protein kinase A regulatory subunit binding; receptor binding;
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