Recombinant Human ALDH1L1, His-tagged

• Cat.No.: ALDH1L1-9554H
• Product Overview: Recombinant Human ALDH1L1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 157-505a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ALDH1L1 aldehyde dehydrogenase 1 family, member L1 [ Homo sapiens ]
• Official Symbol: ALDH1L1
• Synonyms: ALDH1L1; aldehyde dehydrogenase 1 family, member L1; formyltetrahydrofolate dehydrogenase , FTHFD; cytosolic 10-formyltetrahydrofolate dehydrogenase; 10 fTHF; cytosolic 10 formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase; aldehyde dehydrogenase family 1 member L1; FDH; FTHFD; 10-fTHF; DKFZp781N0997
• Gene ID: 10840
• mRNA Refseq: NM_012190
• Protein Refseq: NP_036322
• MIM: 600249
• UniProt ID: O75891
• Chromosome Location: 3q21.2
• Pathway: One Carbon Metabolism, organism-specific biosystem; One carbon pool by folate, organism-specific biosystem; One carbon pool by folate, conserved biosystem
• Function: acyl carrier activity; catalytic activity; cofactor binding; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; methyltransferase activity; oxidoreductase activity; oxidoreductase activity, acting on t