Recombinant Human ALKBH3, GST-tagged
Cat.No. : | ALKBH3-9584H |
Product Overview : | Recombinant Human ALKBH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]). |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-139a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ALKBH3 alkB, alkylation repair homolog 3 (E. coli) [ Homo sapiens ] |
Official Symbol : | ALKBH3 |
Synonyms : | ALKBH3; alkB, alkylation repair homolog 3 (E. coli); alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC 1; prostate cancer antigen 1; prostate cancer antigen-1; alkylated DNA repair protein alkB homolog 3; ABH3; PCA1; DEPC1; DEPC-1; FLJ43614; MGC118790; MGC118792; MGC118793; |
Gene ID : | 221120 |
mRNA Refseq : | NM_139178 |
Protein Refseq : | NP_631917 |
MIM : | 610603 |
UniProt ID : | Q96Q83 |
Chromosome Location : | 11p11.2 |
Pathway : | ABH3 mediated Reversal of Alkylation Damage, organism-specific biosystem; DNA Damage Reversal, organism-specific biosystem; DNA Repair, organism-specific biosystem; Reversal of Alkylation Damage By DNA Dioxygenases, organism-specific biosystem; |
Function : | DNA-N1-methyladenine dioxygenase activity; L-ascorbic acid binding; cytosine C-5 DNA demethylase activity; ferrous iron binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular o |
Products Types
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ALKBH3-2544H | Recombinant Human ALKBH3 Protein, MYC/DDK-tagged | +Inquiry |
ALKBH3-287R | Recombinant Rat ALKBH3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ALKBH3-8901HCL | Recombinant Human ALKBH3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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