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Recombinant Human APCS, GST-tagged

Cat.No.: APCS-9734H
Product Overview: Recombinant Human APCS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Source: E.coli
Species: Human
Tag: GST
Protein length: 20-223a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: APCS amyloid P component, serum [ Homo sapiens ]
Official Symbol: APCS
Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP; pentaxin-related; 9.5S alpha-1-glycoprotein;
Gene ID: 325
mRNA Refseq: NM_001639
Protein Refseq: NP_001630
MIM: 104770
UniProt ID: P02743
Chromosome Location: 1q21-q23
Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem;
Function: metal ion binding; sugar binding; unfolded protein binding;

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