Recombinant Human APLP1, GST-tagged

• Cat.No.: APLP1-9745H
• Product Overview: Recombinant Human APLP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 55-341a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: APLP1 amyloid beta (A4) precursor-like protein 1 [ Homo sapiens ]
• Official Symbol: APLP1
• Synonyms: APLP1; amyloid beta (A4) precursor-like protein 1; amyloid-like protein 1; amyloid precursor like protein 1; amyloid like protein 1; APLP; APLP-1; amyloid precursor-like protein 1
• Gene ID: 333
• mRNA Refseq: NM_001024807
• Protein Refseq: NP_001019978
• MIM: 104775
• UniProt ID: P51693
• Chromosome Location: 19q
• Function: alpha-2A adrenergic receptor binding; alpha-2B adrenergic receptor binding; alpha-2C adrenergic receptor binding; heparin binding; identical protein binding; protein binding; transition metal ion binding