Recombinant Human ARF1, GST-tagged

• Cat.No.: ARF1-9799H
• Product Overview: Recombinant Human ARF1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-181a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARF1 ADP-ribosylation factor 1 [ Homo sapiens ]
• Official Symbol: ARF1
• Synonyms: ARF1; ADP-ribosylation factor 1
• Gene ID: 375
• mRNA Refseq: NM_001024226
• Protein Refseq: NP_001019397
• MIM: 103180
• UniProt ID: P84077
• Chromosome Location: 1q42.13
• Pathway: Arf1 pathway, organism-specific biosystem; Arf6 downstream pathway, organism-specific biosystem; COPI Mediated Transport, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Disease, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding; receptor signaling protein activity