Recombinant Human ASCC1, GST-tagged
Cat.No. : | ASCC1-9922H |
Product Overview : | Recombinant Human ASCC1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | N-term-355a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ASCC1 activating signal cointegrator 1 complex subunit 1 [ Homo sapiens ] |
Official Symbol : | ASCC1 |
Synonyms : | ASCC1; activating signal cointegrator 1 complex subunit 1; ASC1p50; CGI 18; Em:AC022392.3; ASC-1 complex subunit P50; trip4 complex subunit p50; p50; CGI-18; |
Gene ID : | 51008 |
mRNA Refseq : | NM_001198798 |
Protein Refseq : | NP_001185727 |
MIM : | 614215 |
UniProt ID : | Q8N9N2 |
Chromosome Location : | 10pter-q25.3 |
Function : | RNA binding; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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