Recombinant Human ASL, GST-tagged
Cat.No. : | ASL-9935H |
Product Overview : | Recombinant Human ASL protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Specification
- Gene Information
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Description : | This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-350a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ASL argininosuccinate lyase [ Homo sapiens ] |
Official Symbol : | ASL |
Synonyms : | ASL; argininosuccinate lyase; arginosuccinase; argininosuccinase; ASAL; |
Gene ID : | 435 |
mRNA Refseq : | NM_000048 |
Protein Refseq : | NP_000039 |
MIM : | 608310 |
UniProt ID : | P04424 |
Chromosome Location : | 7q11.21 |
Pathway : | Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; |
Function : | argininosuccinate lyase activity; argininosuccinate lyase activity; catalytic activity; lyase activity; |
Products Types
◆ Recombinant Protein | ||
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ASL-390H | Recombinant Human ASL Protein, His (Fc)-Avi-tagged | +Inquiry |
ASL-791M | Recombinant Mouse ASL Protein, His (Fc)-Avi-tagged | +Inquiry |
ASL-576H | Recombinant Human ASL, His-GST tagged | +Inquiry |
◆ Lysates | ||
ASL-001HCL | Recombinant Human ASL cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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