Recombinant Human ASNS, GST-tagged

• Cat.No.: ASNS-9938H
• Product Overview: Recombinant Human ASNS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 247-561a.a.
• Description: The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ASNS asparagine synthetase (glutamine-hydrolyzing) [ Homo sapiens ]
• Official Symbol: ASNS
• Synonyms: ASNS; asparagine synthetase (glutamine-hydrolyzing); asparagine synthetase; asparagine synthetase [glutamine-hydrolyzing]; TS11 cell cycle control protein; glutamine-dependent asparagine synthetase; TS11
• Gene ID: 440
• mRNA Refseq: NM_001178075
• Protein Refseq: NP_001171546
• MIM: 108370
• UniProt ID: P08243
• Chromosome Location: 7q21-q31
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Metabolic pathways, organism-specific biosystem
• Function: ATP binding; asparagine synthase (glutamine-hydrolyzing) activity; asparagine synthase (glutamine-hydrolyzing) activity; cofactor binding; ligase activity; nucleotide binding; protein homodimerization activity