Recombinant Human BAAT, GST-tagged BAAT-10119H

Recombinant Human BAAT, GST-tagged


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Recombinant Human BAAT, GST-tagged

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Cat.No. : BAAT-10119H
Product Overview : Recombinant Human BAAT protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-418a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : BAAT bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) [ Homo sapiens ]
Official Symbol : BAAT
Synonyms : BAAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid Coenzyme A: amino acid N acyltransferase (glycine N choloyltransferase); bile acid-CoA:amino acid N-acyltransferase; BAT; long-chain fatty-acyl-CoA hydrolase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); BACAT; FLJ20300; MGC104432;
Gene ID : 570
mRNA Refseq : NM_001127610
Protein Refseq : NP_001121082
MIM : 602938
UniProt ID : Q14032
Chromosome Location : 9q22.3
Pathway : Bile acid and bile salt metabolism, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Biosynthesis of unsaturated fatty acids, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, conserved biosystem; Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate, organism-specific biosystem;
Function : N-acyltransferase activity; carboxylesterase activity; glycine N-choloyltransferase activity; hydrolase activity; palmitoyl-CoA hydrolase activity; thiolester hydrolase activity; transferase activity, transferring acyl groups;

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