Recombinant Human BAG1, His-tagged BAG1-10124H

Recombinant Human BAG1, His-tagged

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Recombinant Human BAG1, His-tagged

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Cat.No. : BAG1-10124H
Product Overview : Recombinant Human BAG1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Source : E.coli
Species : Human
Tag : His
Protein length : C-term-310a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : BAG1 BCL2-associated athanogene [ Homo sapiens ]
Official Symbol : BAG1
Synonyms : BAG1; BCL2-associated athanogene; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-binding protein; receptor-associated protein, 46-KD; Bcl-2 associating athanogene-1 protein; glucocortoid receptor-associated protein RAP46; HAP; RAP46;
Gene ID : 573
mRNA Refseq : NM_001172415
Protein Refseq : NP_001165886
MIM : 601497
UniProt ID : Q99933
Chromosome Location : 9p12
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function : chaperone binding; phosphoprotein binding; protein binding; receptor signaling protein activity;

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