Recombinant Human C4BPB, His-tagged
Cat.No. : | C4BPB-10533H |
Product Overview : | Recombinant Human C4BPB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-251a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | C4BPB complement component 4 binding protein, beta [ Homo sapiens ] |
Official Symbol : | C4BPB |
Synonyms : | C4BPB; complement component 4 binding protein, beta; C4BP, complement component 4 binding protein, beta; C4b-binding protein beta chain; C4b binding protein; beta chain; complement component 4 binding protein; C4BP; |
Gene ID : | 725 |
mRNA Refseq : | NM_000716 |
Protein Refseq : | NP_000707 |
MIM : | 120831 |
UniProt ID : | P20851 |
Chromosome Location : | 1q32 |
Pathway : | Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Pertussis, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
C4BPB-474H | Recombinant Human C4BPB Protein, His (Fc)-Avi-tagged | +Inquiry |
C4BPB-0054H | Recombinant Human C4BPB Protein, GST-Tagged | +Inquiry |
C4BPB-137H | Recombinant Human C4BPB Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
C4BPB-26312TH | Recombinant Human C4BPB | +Inquiry |
C4BPB-6970H | Recombinant Human Complement Component 4 Binding Protein, Beta, His-tagged | +Inquiry |
◆ Native Protein | ||
C4BPB-184H | Native Human C4b-Binding Protein | +Inquiry |
◆ Lysates | ||
C4BPB-8036HCL | Recombinant Human C4BPB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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