"CACNA2D3" Related Products

Recombinant Human CACNA2D3, GST-tagged

Cat.No.: CACNA2D3-10636H
Product Overview: Recombinant Human CACNA2D3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Source: E.coli
Species: Human
Tag: GST
Protein length: C-term-305a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 [ Homo sapiens ]
Official Symbol: CACNA2D3
Synonyms: CACNA2D3; calcium channel, voltage-dependent, alpha 2/delta subunit 3; voltage-dependent calcium channel subunit alpha-2/delta-3; HSA272268; calcium channel alpha2-delta3 subunit; voltage-gated calcium channel subunit alpha-2/delta-3; calcium channel, voltage-dependent, alpha 2/delta 3 subunit;
Gene ID: 55799
mRNA Refseq: NM_018398
Protein Refseq: NP_060868
MIM: 606399
UniProt ID: Q8IZS8
Chromosome Location: 3p21.1
Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem;
Function: metal ion binding; voltage-gated calcium channel activity; voltage-gated ion channel activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.