Recombinant Human CACNG4, GST-tagged

• Cat.No.: CACNG4-10644H
• Product Overview: Recombinant Human CACNG4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 200-327a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CACNG4 calcium channel, voltage-dependent, gamma subunit 4 [ Homo sapiens ]
• Official Symbol: CACNG4
• Synonyms: CACNG4; calcium channel, voltage-dependent, gamma subunit 4; voltage-dependent calcium channel gamma-4 subunit; MGC11138; MGC24983; TARP gamma-4; transmembrane AMPAR regulatory protein gamma-4; neuronal voltage-gated calcium channel gamma-4 subunit
• Gene ID: 27092
• mRNA Refseq: NM_014405
• Protein Refseq: NP_055220
• MIM: 606404
• UniProt ID: Q9UBN1
• Chromosome Location: 17q24
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem
• Function: voltage-gated calcium channel activity; voltage-gated ion channel activity