Recombinant Human CFL2, GST-tagged CFL2-11143H

Recombinant Human CFL2, GST-tagged

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Recombinant Human CFL2, GST-tagged

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Cat.No. : CFL2-11143H
Product Overview : Recombinant Human CFL2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-166a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CFL2 cofilin 2 (muscle) [ Homo sapiens ]
Official Symbol : CFL2
Synonyms : CFL2; cofilin 2 (muscle); cofilin-2; cofilin, muscle isoform; NEM7;
Gene ID : 1073
mRNA Refseq : NM_001243645
Protein Refseq : NP_001230574
MIM : 601443
UniProt ID : Q9Y281
Chromosome Location : 14q13.2
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; G13 Signaling Pathway, organism-specific biosystem; Pertussis, organism-specific biosystem;
Function : actin binding; protein binding;

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