Recombinant Human CFL2, GST-tagged
Cat.No. : | CFL2-11143H |
Product Overview : | Recombinant Human CFL2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-166a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CFL2 cofilin 2 (muscle) [ Homo sapiens ] |
Official Symbol : | CFL2 |
Synonyms : | CFL2; cofilin 2 (muscle); cofilin-2; cofilin, muscle isoform; NEM7; |
Gene ID : | 1073 |
mRNA Refseq : | NM_001243645 |
Protein Refseq : | NP_001230574 |
MIM : | 601443 |
UniProt ID : | Q9Y281 |
Chromosome Location : | 14q13.2 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; G13 Signaling Pathway, organism-specific biosystem; Pertussis, organism-specific biosystem; |
Function : | actin binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
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Cfl2-881M | Recombinant Mouse Cfl2 Protein, MYC/DDK-tagged | +Inquiry |
CFL2-1174H | Recombinant Human CFL2 Protein, GST-Tagged | +Inquiry |
CFL2-829R | Recombinant Rhesus monkey CFL2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CFL2-7554HCL | Recombinant Human CFL2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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