"CHN1" Related Products

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Recombinant Human CHN1, GST-tagged

Cat.No.: CHN1-11192H
Product Overview: Recombinant Human CHN1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duanes retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: N-term-350a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: CHN1 chimerin (chimaerin) 1 [ Homo sapiens ]
Official Symbol: CHN1
Synonyms: CHN1; chimerin (chimaerin) 1; CHN, Duane retraction syndrome 2 , DURS2; N-chimaerin; ARHGAP2; Chimerin 1 (GTPase activating protein; rho; 2); n chimerin; RhoGAP2; n-chimerin; A-chimaerin; a2-chimaerin; alpha-chimerin; Rho GTPase-activating protein 2; NC; CHN; DURS2; RHOGAP2;
Gene ID: 1123
mRNA Refseq: NM_001025201
Protein Refseq: NP_001020372
MIM: 118423
UniProt ID: P15882
Chromosome Location: 2q31-q32.1
Pathway: Regulation of RAC1 activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem;
Function: GTPase activator activity; SH3/SH2 adaptor activity; ephrin receptor binding; metal ion binding;

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