Recombinant Human CHN1, GST-tagged CHN1-11192H

Recombinant Human CHN1, GST-tagged


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Recombinant Human CHN1, GST-tagged

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Cat.No. : CHN1-11192H
Product Overview : Recombinant Human CHN1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duanes retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : N-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CHN1 chimerin (chimaerin) 1 [ Homo sapiens ]
Official Symbol : CHN1
Synonyms : CHN1; chimerin (chimaerin) 1; CHN, Duane retraction syndrome 2 , DURS2; N-chimaerin; ARHGAP2; Chimerin 1 (GTPase activating protein; rho; 2); n chimerin; RhoGAP2; n-chimerin; A-chimaerin; a2-chimaerin; alpha-chimerin; Rho GTPase-activating protein 2; NC; CHN; DURS2; RHOGAP2;
Gene ID : 1123
mRNA Refseq : NM_001025201
Protein Refseq : NP_001020372
MIM : 118423
UniProt ID : P15882
Chromosome Location : 2q31-q32.1
Pathway : Regulation of RAC1 activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem;
Function : GTPase activator activity; SH3/SH2 adaptor activity; ephrin receptor binding; metal ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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