Recombinant Human CHSY1, GST-tagged CHSY1-11235H

Recombinant Human CHSY1, GST-tagged

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Recombinant Human CHSY1, GST-tagged

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Cat.No. : CHSY1-11235H
Product Overview : Recombinant Human CHSY1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome.
Source : E.coli
Species : Human
Tag : GST
Protein length : 449-802a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CHSY1 chondroitin sulfate synthase 1 [ Homo sapiens ]
Official Symbol : CHSY1
Synonyms : CHSY1; chondroitin sulfate synthase 1; carbohydrate (chondroitin) synthase 1; CSS1; KIAA0990; chondroitin synthase 1; carbohydrate synthase 1; chondroitin glucuronyltransferase 1; N-acetylgalactosaminyltransferase II; chondroitin glucuronyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; CHSY; TPBS; ChSy-1; FLJ58581; DKFZp434M032;
Gene ID : 22856
mRNA Refseq : NM_014918
Protein Refseq : NP_055733
MIM : 608183
UniProt ID : Q86X52
Chromosome Location : 15q26.3
Pathway : Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, organism-specific biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, conserved biosystem; Metabolic pathways, organism-specific biosystem; chondroitin and dermatan biosynthesis, organism-specific biosystem; chondroitin and dermatan biosynthesis, conserved biosystem;
Function : N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; metal ion binding; transferase activity; transferase activity, transferring he

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