Recombinant Human CHSY1, GST-tagged
Cat.No. : | CHSY1-11235H |
Product Overview : | Recombinant Human CHSY1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 449-802a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CHSY1 chondroitin sulfate synthase 1 [ Homo sapiens ] |
Official Symbol : | CHSY1 |
Synonyms : | CHSY1; chondroitin sulfate synthase 1; carbohydrate (chondroitin) synthase 1; CSS1; KIAA0990; chondroitin synthase 1; carbohydrate synthase 1; chondroitin glucuronyltransferase 1; N-acetylgalactosaminyltransferase II; chondroitin glucuronyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; CHSY; TPBS; ChSy-1; FLJ58581; DKFZp434M032; |
Gene ID : | 22856 |
mRNA Refseq : | NM_014918 |
Protein Refseq : | NP_055733 |
MIM : | 608183 |
UniProt ID : | Q86X52 |
Chromosome Location : | 15q26.3 |
Pathway : | Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, organism-specific biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, conserved biosystem; Metabolic pathways, organism-specific biosystem; chondroitin and dermatan biosynthesis, organism-specific biosystem; chondroitin and dermatan biosynthesis, conserved biosystem; |
Function : | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; metal ion binding; transferase activity; transferase activity, transferring he |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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