Recombinant Human CHSY1, GST-tagged


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Recombinant Human CHSY1, GST-tagged

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Cat.No. : CHSY1-11235H
Product Overview : Recombinant Human CHSY1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome.
Source : E.coli
Species : Human
Tag : GST
Protein length : 449-802a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CHSY1 chondroitin sulfate synthase 1 [ Homo sapiens ]
Official Symbol : CHSY1
Synonyms : CHSY1; chondroitin sulfate synthase 1; carbohydrate (chondroitin) synthase 1; CSS1; KIAA0990; chondroitin synthase 1; carbohydrate synthase 1; chondroitin glucuronyltransferase 1; N-acetylgalactosaminyltransferase II; chondroitin glucuronyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; CHSY; TPBS; ChSy-1; FLJ58581; DKFZp434M032;
Gene ID : 22856
mRNA Refseq : NM_014918
Protein Refseq : NP_055733
MIM : 608183
UniProt ID : Q86X52
Chromosome Location : 15q26.3
Pathway : Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, organism-specific biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, conserved biosystem; Metabolic pathways, organism-specific biosystem; chondroitin and dermatan biosynthesis, organism-specific biosystem; chondroitin and dermatan biosynthesis, conserved biosystem;
Function : N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; metal ion binding; transferase activity; transferase activity, transferring he
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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