Recombinant Human CLDN3, GST-tagged CLDN3-11295H

Recombinant Human CLDN3, GST-tagged

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Recombinant Human CLDN3, GST-tagged

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Cat.No. : CLDN3-11295H
Product Overview : Recombinant Human CLDN3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-220a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CLDN3 claudin 3 [ Homo sapiens ]
Official Symbol : CLDN3
Synonyms : CLDN3; claudin 3; C7orf1, CPETR2; claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; HRVP1; RVP1; ventral prostate.1 like protein; CPE-R 2; CPE-receptor 2; ventral prostate.1-like protein; ventral prostate.1 protein homolog; C7orf1; CPE-R2; CPETR2;
Gene ID : 1365
mRNA Refseq : NM_001306
Protein Refseq : NP_001297
MIM : 602910
UniProt ID : O15551
Chromosome Location : 7q11
Pathway : Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
Function : identical protein binding; structural molecule activity; transmembrane signaling receptor activity;

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