Recombinant Human CNGA3, His-tagged


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Recombinant Human CNGA3, His-tagged

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Cat.No. : CNGA3-11377H
Product Overview : Recombinant Human CNGA3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
Source : E.coli
Species : Human
Tag : His
Protein length : 590-694a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : CNGA3 cyclic nucleotide gated channel alpha 3 [ Homo sapiens ]
Official Symbol : CNGA3
Synonyms : CNGA3; cyclic nucleotide gated channel alpha 3; ACHM2, CNCG3; cyclic nucleotide-gated cation channel alpha-3; CCNC1; CCNCa; CNG3; CNG-3; CNG channel alpha-3; cyclic nucleotide-gated channel alpha-3; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; ACHM2; CNCG3; CCNCalpha;
Gene ID : 1261
mRNA Refseq : NM_001079878
Protein Refseq : NP_001073347
MIM : 600053
UniProt ID : Q16281
Chromosome Location : 2q11.2
Pathway : Olfactory transduction, organism-specific biosystem; Olfactory transduction, conserved biosystem; Visual signal transduction: Cones, organism-specific biosystem;
Function : cGMP binding; intracellular cyclic nucleotide activated cation channel activity; ion channel activity; ligand-gated ion channel activity; nucleotide binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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