Recombinant Human COL4A6, GST-tagged COL4A6-11436H

Recombinant Human COL4A6, GST-tagged


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Recombinant Human COL4A6, GST-tagged

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Cat.No. : COL4A6-11436H
Product Overview : Recombinant Human COL4A6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-73a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : COL4A6 collagen, type IV, alpha 6 [ Homo sapiens ]
Official Symbol : COL4A6
Synonyms : COL4A6; collagen, type IV, alpha 6; collagen alpha-6(IV) chain; collagen alpha 6 type IV; collagen IV, alpha-6 polypeptide; dJ889N15.4 (Collagen Alpha 6(IV)); collagen of basement membrane, alpha-6; DELXq22.3; CXDELq22.3; MGC88184;
Gene ID : 1288
mRNA Refseq : NM_001847
Protein Refseq : NP_001838
MIM : 303631
UniProt ID : Q14031
Chromosome Location : Xq22
Pathway : Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Function : binding; extracellular matrix structural constituent;

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