Recombinant Human COL6A1, His-tagged COL6A1-11438H

Recombinant Human COL6A1, His-tagged

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Recombinant Human COL6A1, His-tagged

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Cat.No. : COL6A1-11438H
Product Overview : Recombinant Human COL6A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Source : E.coli
Species : Human
Tag : His
Protein length : 770-1028a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : COL6A1 collagen, type VI, alpha 1 [ Homo sapiens ]
Official Symbol : COL6A1
Synonyms : COL6A1; collagen, type VI, alpha 1; collagen alpha-1(VI) chain; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide; OPLL;
Gene ID : 1291
mRNA Refseq : NM_001848
Protein Refseq : NP_001839
MIM : 120220
UniProt ID : P12109
Chromosome Location : 21q22.3
Pathway : Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem;
Function : platelet-derived growth factor binding;

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