Recombinant Human COL9A1, GST-tagged COL9A1-11442H

Recombinant Human COL9A1, GST-tagged


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Recombinant Human COL9A1, GST-tagged

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Cat.No. : COL9A1-11442H
Product Overview : Recombinant Human COL9A1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 20-328a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : COL9A1 collagen, type IX, alpha 1 [ Homo sapiens ]
Official Symbol : COL9A1
Synonyms : COL9A1; collagen, type IX, alpha 1; collagen alpha-1(IX) chain; alpha-1(IX) collagen chain; collagen IX, alpha-1 polypeptide; cartilage-specific short collagen; MED; EDM6; STL4; DJ149L1.1.2; FLJ40263;
Gene ID : 1297
mRNA Refseq : NM_001851
Protein Refseq : NP_001842
MIM : 120210
UniProt ID : P20849
Chromosome Location : 6q12-q14
Pathway : Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Signal Transduction, organism-specific biosystem;
Function : extracellular matrix structural constituent conferring tensile strength; metal ion binding; structural molecule activity;

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