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Recombinant Human CRABP2, GST-tagged

Cat.No.: CRABP2-11551H
Product Overview: Recombinant Human CRABP2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-138a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: CRABP2 cellular retinoic acid binding protein 2 [ Homo sapiens ]
Official Symbol: CRABP2
Synonyms: CRABP2; cellular retinoic acid binding protein 2; cellular retinoic acid-binding protein 2; CRABP II; cellular retinoic acid-binding protein II; RBP6; CRABP-II;
Gene ID: 1382
mRNA Refseq: NM_001199723
Protein Refseq: NP_001186652
MIM: 180231
UniProt ID: P29373
Chromosome Location: 1q21.3
Pathway: Vitamin A and carotenoid metabolism, organism-specific biosystem;
Function: lipid binding; retinal binding; retinoic acid binding; retinoid binding; retinol binding; transporter activity;

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