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Recombinant Human CTSH, GST-tagged

Cat.No.: CTSH-11688H
Product Overview: Recombinant Human CTSH protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
Source: E.coli
Species: Human
Tag: GST
Protein length: 58-289a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: CTSH cathepsin H [ Homo sapiens ]
Official Symbol: CTSH
Synonyms: CTSH; cathepsin H; CPSB; pro-cathepsin H; ACC 4; ACC 5; aleurain; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; ACC-4; ACC-5; minichain; MGC1519; DKFZp686B24257;
Gene ID: 1512
mRNA Refseq: NM_004390
Protein Refseq: NP_004381
MIM: 116820
UniProt ID: P09668
Chromosome Location: 15q25.1
Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Function: HLA-A specific activating MHC class I receptor activity; aminopeptidase activity; apoptotic protease activator activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; kininogen binding; peptidase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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