Recombinant Human DAO, GST-tagged

• Cat.No.: DAO-11821H
• Product Overview: Recombinant Human DAO protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 24-347a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DAO D-amino-acid oxidase [ Homo sapiens ]
• Official Symbol: DAO
• Synonyms: DAO; D-amino-acid oxidase; DAMOX; D-amino acid oxidase; DAAO; OXDA; MGC35381
• Gene ID: 1610
• mRNA Refseq: NM_001917
• Protein Refseq: NP_001908
• MIM: 124050
• UniProt ID: P14920
• Chromosome Location: 12
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; D-Arginine and D-ornithine metabolism, organism-specific biosystem; D-Arginine and D-ornithine metabolism, conserved biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Glyoxylate metabolism, organism-specific biosystem
• Function: D-amino-acid oxidase activity; D-amino-acid oxidase activity; FAD binding; nucleotide binding; oxidoreductase activity; protein binding; protein dimerization activity