Recombinant Human DCI, GST-tagged

• Cat.No.: DCI-11852H
• Product Overview: Recombinant Human DCI protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-302a.a.
• Description: This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ECI1 enoyl-CoA delta isomerase 1 [ Homo sapiens ]
• Official Symbol: ECI1
• Synonyms: ECI1; enoyl-CoA delta isomerase 1; DCI, dodecenoyl CoA isomerase , dodecenoyl Coenzyme A delta isomerase (3,2 trans enoyl Coenzyme A isomerase); enoyl-CoA delta isomerase 1, mitochondrial; 3; 2 trans enoyl CoA isomerase; dodecenoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; acetylene-allene isomerase; 3,2 trans-enoyl-CoA isomerase; delta3, delta2-enoyl-CoA isomerase; 3,2 trans-enoyl-Coenzyme A isomerase; delta(3),Delta(2)-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase, mitochondrial; dodecenoyl-CoA delta isomerase (3,2 trans-enoyl-CoA isomerase); dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase); DCI
• Gene ID: 1632
• mRNA Refseq: NM_001178029
• Protein Refseq: NP_001171500
• MIM: 600305
• UniProt ID: P42126
• Chromosome Location: 16p13.3
• Pathway: Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Fatty Acid Beta-Oxidation, organism-specific biosystem
• Function: dodecenoyl-CoA delta-isomerase activity; dodecenoyl-CoA delta-isomerase activity; identical protein binding; intramolecular oxidoreductase activity