Recombinant Human DCI, GST-tagged
Cat.No. : | DCI-11852H |
Product Overview : | Recombinant Human DCI protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-302a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ECI1 enoyl-CoA delta isomerase 1 [ Homo sapiens ] |
Official Symbol : | ECI1 |
Synonyms : | ECI1; enoyl-CoA delta isomerase 1; DCI, dodecenoyl CoA isomerase , dodecenoyl Coenzyme A delta isomerase (3,2 trans enoyl Coenzyme A isomerase); enoyl-CoA delta isomerase 1, mitochondrial; 3; 2 trans enoyl CoA isomerase; dodecenoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; acetylene-allene isomerase; 3,2 trans-enoyl-CoA isomerase; delta3, delta2-enoyl-CoA isomerase; 3,2 trans-enoyl-Coenzyme A isomerase; delta(3),Delta(2)-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase, mitochondrial; dodecenoyl-CoA delta isomerase (3,2 trans-enoyl-CoA isomerase); dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase); DCI; |
Gene ID : | 1632 |
mRNA Refseq : | NM_001178029 |
Protein Refseq : | NP_001171500 |
MIM : | 600305 |
UniProt ID : | P42126 |
Chromosome Location : | 16p13.3 |
Pathway : | Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Fatty Acid Beta-Oxidation, organism-specific biosystem; |
Function : | dodecenoyl-CoA delta-isomerase activity; dodecenoyl-CoA delta-isomerase activity; identical protein binding; intramolecular oxidoreductase activity; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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