"DGKB" Related Products

Recombinant Human DGKB, His-tagged

Cat.No.: DGKB-11954H
Product Overview: Recombinant Human DGKB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 30-140a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: DGKB diacylglycerol kinase, beta 90kDa [ Homo sapiens ]
Official Symbol: DGKB
Synonyms: DGKB; diacylglycerol kinase, beta 90kDa; DAGK2, diacylglycerol kinase, beta (90kD); diacylglycerol kinase beta; DGK; DGK BETA; KIAA0718; DAG kinase beta; diglyceride kinase beta; 90 kDa diacylglycerol kinase; DAGK2; DGK-BETA;
Gene ID: 1607
mRNA Refseq: NM_004080
Protein Refseq: NP_004071
MIM: 604070
UniProt ID: Q9Y6T7
Chromosome Location: 7p21.2
Pathway: Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem;
Function: ATP binding; calcium ion binding; diacylglycerol kinase activity; nucleotide binding; transferase activity;

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