Recombinant Human DHPS, GST-tagged

• Cat.No.: DHPS-11970H
• Product Overview: Recombinant Human DHPS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-369a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DHPS deoxyhypusine synthase [ Homo sapiens ]
• Official Symbol: DHPS
• Synonyms: DHPS; deoxyhypusine synthase; MIG13; migration inducing gene 13; migration-inducing gene 13; DS; DHS
• Gene ID: 1725
• mRNA Refseq: NM_001206974
• Protein Refseq: NP_001193903
• MIM: 600944
• UniProt ID: P49366
• Chromosome Location: 19p13.2
• Pathway: Hypusine synthesis from eIF5A-lysine, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; hypusine biosynthesis, organism-specific biosystem; hypusine biosynthesis, conserved biosystem
• Function: deoxyhypusine synthase activity; protein binding; transferase activity