"DIAPH3" Related Products


Recombinant Human DIAPH3, GST-tagged

Cat.No.: DIAPH3-11993H
Product Overview: Recombinant Human DIAPH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: C-term-350a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: DIAPH3 diaphanous homolog 3 (Drosophila) [ Homo sapiens ]
Official Symbol: DIAPH3
Synonyms: DIAPH3; diaphanous homolog 3 (Drosophila); auditory neuropathy, autosomal dominant 1 , AUNA1, diaphanous (Drosophila, homolog) 3; protein diaphanous homolog 3; AN; DRF3; FLJ34705; NSDAN; diaphanous-related formin 3; diaphanous-related formin-3; auditory neuropathy, autosomal dominant 1; DIA2; AUNA1; diap3; mDia2; DKFZp434C0931; DKFZp686A13178;
Gene ID: 81624
mRNA Refseq: NM_001042517
Protein Refseq: NP_001035982
MIM: 614567
UniProt ID: Q9NSV4
Chromosome Location: 13q21.2
Pathway: CDC42 signaling events, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem;
Function: Rho GTPase binding; actin binding; binding;

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