Recombinant Full Length Human DIAPH3 Protein, GST-tagged

• Cat.No.: DIAPH3-2558HF
• Product Overview: Human DIAPH3 full-length ORF ( NP_112194.2, 1 a.a. - 849 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 124.5 kDa
• Protein Length: 849 amino acids
• AA Sequence: MSEERSLSLLAKAVDPRHPNMMTDV VKLLSAVCIVGEESILEEVLEALTS AGEEKKIDRFFCIVEGLRHNSVQLQ VACMQLINALVTSPDDLDFRLHIRN EFMRCGLKEILPNLKCIKNDGLDIQ LKVFDEHKEEDLFELSHRLEDIRAE LDEAYDVYNMVWSTVKETRAEGYFI SILQHLLLIRNDYFIRQQYFKLIDE CVSQIVLHRDGMDPDFTYRKRLDLD LTQFVDICIDQAKLEEFEEKASELY KKFEKEFTDHQETQAELQKKEAKIN ELQAELQAFKSQFGALPADCNIPLP PSKEGGTGHSALPPPPPLPSGGGVP PPPPPPPPPPLPGMRMPFSGPVPPP PPLGFLGGQNSPPLPILPFGLKPKK EFKPEISMRRLNWLKIRPHEMTENC FWIKVNENKYENVDLLCKLENTFCC QQKERREEEDIEEKKSIKKKIKELK FLDSKIAQNLSIFLSSFRVPYEEIR MMILEVDETRLAESMIQNLIKHLPD QEQLNSLSQFKSEYSNLCEPEQFVV VMSNVKRLRPRLSAILFKLQFEEQV NNIKPDIMAVSTACEEIKKSKSFSK LLELVLLMGNYMNAGSRNAQTFGFN LSSLCKLKDTKSADQKTTLLHFLVE ICEEKYPDILNFVDDLEPLDKASKV SVETLEKNLRQMGRQLQQLEKELET FPPPEDLHDKFVTKMSRFVISAKEQ YETLSKLHENMEKLYQSIIGYYAID VKKVSVEDFLTDLNNFRTTFMQAIK ENIKKREAEEKEKRVRIAKELAERE RLERQQKKKRLLEMKTEGDETGVMD NLLEALQSGAAFRDRRKRTPMPKDV RQSLSPMSQRPVLKVCNHGNKPYL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DIAPH3 diaphanous homolog 3 (Drosophila) [ Homo sapiens ]
• Official Symbol: DIAPH3
• Synonyms: DIAPH3; diaphanous homolog 3 (Drosophila); auditory neuropathy, autosomal dominant 1 , AUNA1, diaphanous (Drosophila, homolog) 3; protein diaphanous homolog 3; AN; DRF3; FLJ34705; NSDAN; diaphanous-related formin 3; diaphanous-related formin-3; auditory neuropathy, autosomal dominant 1; DIA2; AUNA1; diap3; mDia2; DKFZp434C0931; DKFZp686A13178
• Gene ID: 81624
• mRNA Refseq: NM_001042517
• Protein Refseq: NP_001035982
• MIM: 614567
• UniProt ID: Q9NSV4