Recombinant Human DKK2, His-tagged

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Recombinant Human DKK2, His-tagged

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Cat.No. : DKK2-12012H
Product Overview : Recombinant Human DKK2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Source : E.coli
Species : Human
Tag : His
Protein length : 1-259a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : DKK2 dickkopf 2 homolog (Xenopus laevis) [ Homo sapiens ]
Official Symbol : DKK2
Synonyms : DKK2; dickkopf 2 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 2; dickkopf-related protein 2; hDkk-2; dickkopf-2; dickkopf homolog 2; dickkopf related protein-2; DKK-2;
Gene ID : 27123
mRNA Refseq : NM_014421
Protein Refseq : NP_055236
MIM : 605415
UniProt ID : Q9UBU2
Chromosome Location : 4q25
Pathway : Presenilin action in Notch and Wnt signaling, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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