Recombinant Human DNAJB11, His-tagged

• Cat.No.: DNAJB11-12059H
• Product Overview: Recombinant Human DNAJB11 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 23-358a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 [ Homo sapiens ]
• Official Symbol: DNAJB11
• Synonyms: DNAJB11; DnaJ (Hsp40) homolog, subfamily B, member 11; dnaJ homolog subfamily B member 11; EDJ; ERdj3; HEDJ; DnaJ protein 9; human DnaJ protein 9; dnaJ protein homolog 9; APOBEC1-binding protein 2; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; DJ9; Dj-9; ERj3; ABBP2; ERj3p; hDj-9; ABBP-2; UNQ537; PRO1080
• Gene ID: 51726
• mRNA Refseq: NM_016306
• Protein Refseq: NP_057390
• MIM: 611341
• UniProt ID: Q9UBS4
• Chromosome Location: 3q27
• Pathway: Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Unfolded Protein Response, organism-specific biosystem
• Function: heat shock protein binding; unfolded protein binding